Research | The Welch Center

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Happy Family

Decades of

RESEARCH

Dive into the science behind Emotional Connection

2024

Translation, cross-cultural adaptation and validation of the universal Welch Emotional Connection Screen using primary and bilingual Spanish-speaking coders of videotaped mother-child interactions

Fantastic voyage: Chasing oxytocin from the bedside to the bench and back again

Preschool-based mother-child emotional preparation program improves emotional connection, behavior regulation in the home and classroom: a randomized controlled trial

Qualitative insights from a randomized clinical trial of a mother-child emotional preparation program for preschool-aged children

Assessment of Neurodevelopment in Infants With and Without Exposure to Asymptomatic or Mild Maternal SARS-CoV-2 Infection During Pregnancy

Pandemic beyond the virus: maternal COVID-related postnatal stress is associated with infant temperament

Facilitating early parent-infant emotional connection improves cortical networks in preterm infants

A Novel Method for ECG Artifact Removal from EEG without Simultaneous ECG

Wired to Connect: The Autonomic Socioemotional Reflex Arc

Family nurture intervention increases term age forebrain EEG activity: A multicenter replication trial

Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection

Effects of Family Nurture Intervention in the NICU on Theory of Mind Abilities in Children Born Very Preterm: A Randomized Controlled Trial

Preterm infant heart rate is lowered after Family Nurture Intervention in the NICU: Evidence in support of autonomic conditioning

The Welch Emotional Connection Screen (WECS) training in Pediatric Residency

How babies learn-The autonomic socioemotional reflex

A review of newborn outcomes during the COVID-19 pandemic

FNI-NICU increases autonomic regulation in mothers and children at 4-5 years of age- Follow-up results from an RCT

The practical utility of the Welch Emotional Connection Screen for rating parent-infant relational health

Family nurture intervention alters relationships between preterm infant EEG delta brush characteristics and term age EEG power

2019

Early Life Maternal Separation and Maternal Behaviour Modulate Acoustic Characteristics of Rat Pup Ultrasonic Vocalizations

Nurturescience versus neuroscience- A case for rethinking perinatal mother-infant behaviors and relationship

Darwin's Other Dilemmas and the Theoretical Roots of Emotional Connection

Autonomic regulation of preterm infants is enhanced by Family Nurture Intervention

Validation of WECS at infant age 6 mo is associated with child behavioural problems at 3 years

Perinatal antibiotics alter preterm infant EEG and neurobehavior in the Family Nurture Intervention trial

The Welch Emotional Connection Screen: validation of a brief mother-infant relational health screen

2018

Integrated information in the EEG of preterm infants increases with family nurture intervention, age, and conscious state

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum

FNI-NICU increases positive mother-infant face-to-face engagement at 4 months 2

2017

Increased trophoblast inclusions in placentas-risk ofr preterm neurodevelopmental outcomes

Family nurture intervention in preterm infants increases early development of cortical activity and independence of regional power trajectories

Enteric serotonin and oxytocin endogenous regulation of severity in a murine model of necrotizing enterocolitis.

Dopamine neuron dependent behaviors mediated by glutamate cotransmission

Colostrum OT modulates cellular stress response, inflammation, and autophagy markers in newborn rat gut villi

Calming Cycle Theory and the co-regulation of Oxytocin

2016

Calming cycle theory: the role of visceral/autonomic learning in early mother and infant/child behaviour and development

Nurture in the neonatal intensive care unit

Advances in family based care in the neonatal ICU

Oxytocin opposes effects of bacterial endotoxin on ER-stress signaling in Caco2BB gut cells

Depression and anxiety symptoms of mothers of preterm infants are decreased at 4 months corrected age with Family Nurture Intervention in the NICU

Prairie vole pups show potentiated isolation-induced vocalizations following isolation from their mother, but not their father

Nurture in the neonatal intensive care unit

2015

Family Nurture Intervention in the Neonatal Intensive Care Unit improves social-relatedness, attention, and neurodevelopment of preterm infants at 18 months in a randomized controlled trial

Variations in maternal behavior in rats selected for infant USV

Family Nurture Intervention in preterm infants alters frontal cortical functional connectivity assessed by EEG coherence

Effects of maternal deprivation and the duration of reunion time on rat pup ultrasonic vocalization responses to isolation: possible implications for human infant studies

Family Nurture Intervention in the Neonatal Intensive Care Unit improves social-relatedness, attention, and neurodevelopment of preterm infants at 18 months in a randomized controlled trial

Family nurture intervention improves the quality of maternal caregiving in the neonatal intensive care unit: evidence from a randomized controlled trial

2014

Oxytocin regulates gastrointestinal motility, inflammation, macromolecular permeability, and mucosal maintenance in mice

Electroencephalographic activity of preterm infants is increased by Family Nurture Intervention: a randomized controlled trial in the NICU

Oxytocin modulates markers of the unfolded protein response in Caco2BB gut cells

2013

Oxytocin modulates mTORC1 pathway in the gut

Randomized controlled trial of Family Nurture Intervention in the NICU: assessments of length of stay, feasibility and safety

2012

Family nurture intervention (FNI): methods and treatment protocol of a randomized controlled trial in the NICU

Cutting the vagus nerve below the diaphragm prevents maternal potentiation of infant rat vocalization

2011

Review: secretin is not effective for the treatment of children with autism spectrum disorders

PI3K/Akt responses to oxytocin stimulation in Caco2BB gut cells.

2010

Combined administration of secretin and oxytocin inhibits chronic colitis and associated activation of forebrain neurons

2009

Expression and developmental regulation of oxytocin (OT) and oxytocin receptors (OTR) in the enteric nervous system (ENS) and intestinal epithelium

2006

Secretin's role in the cerebellum: a larger biological context and implications for developmental disorders

2005

Brain Effects of Chronic IBD in Areas Abnormal in Autism - Treatment by Single Neuropeptides Secretin and Oxytocin

2004

Secretin: hypothalamic distribution and hypothesized neuroregulatory role in autism

2003

Secretin Activates Visceral Brain Regions in the Rat Including Areas Abnormal in Autism

1998

Mother-child holding therapy and autism

1987

Toward prevention of developmental disorders

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